Study of Eosinophil Count in Nasal and Blood Smear in Allergic Respiratory Diseases

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Ravindra Sonawane
Nilesh Ahire
Suhas Patil
Abhijit Korde

Abstract

Introduction: Allergic rhinitis and asthma are two very common allergic diseases of respiratory tract in pediatric patients. In this geographical area, where the prevalence of allergens exists, the role of allergens as the etiological factor is higher in allergic respiratory disorders. Confirmation of allergen as etiologic agent is cumbersome in a small setup, where IgE estimation and allergy tests are not accessible. In this study, the simple test of peripheral smear and nasal smear eosinophil count as a reliable diagnosis to solve the above problem and establishing allergy as etiological agent has been tried. Material and Methods: For the present study which was conducted over 2 years in children between 2 to 12 years who visited tertiary health care center, Nashik. The allergic respiratory cases based on typical history and clinical features were included in the study and investigated for nasal and blood eosinophilia. Children with TB, recurrent and chronic pneumonia, malnutrition, malignancy, collagen vascular disorders and those who are on steroid therapy were excluded from the study. The clinical profile of allergic rhinitis with or without asthma and nasal and blood eosinophils are studied. Result: Out of 100 patients, there was male predominance and incidence was increasing as age increases. Dust is the most common risk factor for allergic rhinitis followed by weather changes, whereas in allergic rhinitis with bronchial asthma, weather change is common risk factor followed by dust and family history. In children with allergic rhinitis with or without bronchial asthma, there is positive relation between nasal and peripheral smear eosinophil count. Conclusion: So, nasal eosinophil count which is simple, non-invasive, economical and reliable can be used as an alternative to invasive peripheral smear eosinophil count as both are equally efficacious in diagnosing allergic respiratory diseases.

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How to Cite
Sonawane, R., Ahire, N., Patil, S., & Korde, A. (2016). Study of Eosinophil Count in Nasal and Blood Smear in Allergic Respiratory Diseases. MVP Journal of Medical Sciences. Retrieved from https://mvpjms.org/index.php/mvpjms/article/view/245

References

  1. Repaport HG. Clemens von Pirquetandalerty. Anu Allergy. 1973; 31:467–75. (ISI Medline).
  2. Ghazi BM, Imamzadehgan R, Mohammadi AA, Darakhshan R, et al. Frequency of allergic rhinitis in school age children (7-18 years) in Tehran. Iranian Journal of Allergy Asthma and Immunology. 2003 Dec; 2(4):181–3.
  3. Kemp A, BryanL. Perenniall rhinitis: A common children complaint. Med J Aust. 1984; 141(10):640–3.
  4. Kumar L, Patil AS, Walia BNS. Clinical profile of bronchial asthma in children living in and around Chandigarh. Indian Pediatr. 1968; 11(4):273–6.
  5. Chowdary VS, Vinaykumar EC, Rao JJ, Rao R, et al. A study of serum IgE and eosinophils in respiratory allergys. Indian J Allergy Asthma Immunol. 2003; 17(1):21–4.
  6. Wakhlu I, Sharma NL. A clinical study of bronchial asthma in children. Indian Pediatr. 1974; 11:789.
  7. Pokharel PK, Pokharel P, Bhatia NK, Pandey RM, Erkki K. Asthma symptomatics school children of Sonapur. Kathamandu University Medical Journal. 2007; 5(4):484–7.
  8. Akbari H, Fana-Hosseini R, Miri S, Amin R. The prevalence of allergic rhinitis among 11-15 years old children in Shiraz. IJI Summer. 2004; 1(2):133–7.
  9. Cosmes E L , Canadillas FG, Martin TS, et al. Value of eosinophilia in blood and nasal exudate in the diagnosis of different types of rhinitis. Allergologia et Immuno pathologia. 1984; 12(4):283–8.
  10. Crobach M, Hermans I, Kaptein A, et al. Nasal smear eosinophilia for the diagnosis of allergic rhinitis and eosinophilic non-allergic rhinitis. Sc and J Primary Health Care. 1996; 14(2):116–21.
  11. Lans DM, Alfeno N, Rocklin R. Nasal eosinophilia in allergic and non-allergic rhinitis: Usefulness of the nasal smear in the diagnosis of allergic rhinitis. Allergy Proceedings. 1989; 10(4):275–80.
  12. Sanil A, Aydin S, Ates G, Eken M, Celebi O. Comparison of nasal smear eosinophilia with skin prick test positivity in patients with allergic rhinitis. Kulak Burun Bogaz Ihtis Derg. 2006; 16(2):60–3.
  13. Miller RE, Paradise JL, Fridat GA, et al. The nasal smear for eosinophils: Its value in children with seasonal allergic rhinitis. Am J Diseases of Children. 1982; 136(11):1009– 111.
  14. Saracli T, Scott RB. Comparative study of simultaneous blood and nasal secretion eosinophilia in children with allergic diseases. The Journal of Asthma Research. 1967 Mar; 4(3):219–27.

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