This was a randomized controlled trial undertaken to study the role of zinc supplementation on growth of low birth weight infants (b.wt≤2500 gm). Out of 120 LBW infants, 23 were excluded due to loss of follow up. The remaining 97 LBW eligible neonates were randomized in to 2 group (zinc & control group), zinc group were given zinc supplementation at a dose of 2 mg/kg/day for 8 weeks from enrollment. They were then followed up every 4 weeks up to 8 weeks. At each visit, detail anthropometry including e weight, length, and head circumference were recorded at each visit. The infants in the zinc group had significantly higher weight gain (p<0.000), length gain (p<0.000), linear growth velocity and head circumference at 8 weeks. We concluded that zinc supplementation at 2 mg/kg/day for 8 weeks in LBW infants improves their growth during infancy.
How to Cite
Sonawane, R., Patil, S., Gulati, L., & Sonawane, S. (2014). To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants. MVP Journal of Medical Sciences, 25–29. Retrieved from https://mvpjms.org/index.php/mvpjms/article/view/6
- Berger A. Science commentary: what does zinc do? Br Med J. 2002 Nov; 325:1062.
- Friel JK, Andrews WL, Mathew JD Long DR, Cornel AM, Cox M et al. Zinc supplementation in very low birth weight infants. J ped gastro nutrition 1993; 17:97–104.
- Díaz-Gomez NM, Domẻnech E, Barroso F, Castells S, Cortabarria C, Jiménez A. The effect of zinc supplementation on linear growth, body consumption, and growth factors in preterm infants. Pediatrics. 2003; 111:1002–9.
- Lira Pic, Ashworth A, Morris SS . Effect of zinc supplementation on the morbidity, immune function, and growth of low birth weight, full term infants in North East Brazil. Am J Clin Nutr. 1998 Aug; 68:418S–24S.
- Islam MN, Chowdhury M, Siddika M, Qurishi SB, Bhuiyan MK, Hoque MM et al. Effect of oral zinc supple- mentation on the growth of preterm infants. Indian Pediatr.2010 Oct 17; 47(10):845–9.
- Sazawal S, Black RE, Menon VP, Dinghra P, Caulfield LE, Dhingra U et al. Zinc supplementation in infants born small for gestational age reduces mortality. Pediatrics. 2001 Dec; 108:1280–6.
- Sur D, Gupta DN, Mondal SK, Ghosh S, Manna B, Rajendran K et al. Impact of zinc supplementation on diarrheal morbidity and growth pattern of low birth weight infants in Kolkata. Indian Pediatr. 2003 Dec; 112(6 Pt 1):1327–32.
- Sazawal S, Black RE. Effect of oral zinc supplementation on growth of preterm infants. Indian Pediatr. 2010 Oct 17; 47:841–2.
- Ram Kumar TV, Ramji S. Effect of zinc supplementation on growth in very low birth weight infants. J Trop Pediatr. 2012; 58(1): 50–4.
- Castiio-Duran C, Rodriguez A, Venegas G, Alvarez P, Icaza G. Zinc supplementation and growth of infants born small for gestational age. J Pediatr. 1995; 127:206–211.
- Hoque A, Ali SMA. Role of zinc in lowbirth weight neonates. Bangladesh Med J. 2009 Jan; 38(1):24–30.
- Taneja S, Bhandari N, Rongsen-Chandola T, Mahalanabis D, Fontaine O, Bhan MK. Effect of zinc supplementation on morbidity and growth in hospital-born, low-birth-weight infants. Am J Clin Nutr. 2009; 90:385–91.